Literature, most generically, is any body of written works. More restrictively, literature writing is considered to be an art form, or any single writing deemed to have artistic or intellectual value, often due to deploying language in ways that differ from ordinary usage.
The death of Dr. Hudson is a loss to the republick of letters.
William King, letter (Jan. 7, 1719). Same phrase occurs in the Spectator. Commonwealth of letters is used by Addison, Spectator, No. 529. Nov. 6, 1712.
Pesticides are used around the world but can persist in the environment, contaminating drinking and irrigation water with toxic organic compounds. One example is Vietnam where herbicides and dioxins applied during the Vietnam war entered the water cycle, possibly leading to cancers and abnormalities in newborn babies.