Bioinformatics ( listen) is an interdisciplinary field that develops methods and software tools for understanding biological data. As an interdisciplinary field of science, bioinformatics combines biology, computer science, mathematics and statistics to analyze and interpret biological data. Bioinformatics has been used for in silico analyses of biological queries using mathematical and statistical techniques.
Biology is the natural science that involves the study of life and living organisms, including their physical structure, chemical composition, function, development and evolution. Modern biology is a vast field, composed of many branches. Despite the broad scope and the complexity of the science, there are certain unifying concepts that consolidate it into a single, coherent field. Biology recognizes the cell as the basic unit of life, genes as the basic unit of heredity, and evolution as the engine that propels the creation of new species. Living organisms are open systems that survive by transforming energy and decreasing their local entropy to maintain a stable and vital condition defined as homeostasis. See glossary of biology.
Computational biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems. The field is broadly defined and includes foundations in biology, applied mathematics, statistics, biochemistry, chemistry, biophysics, molecular biology, genetics, genomics, computer science and evolution.
Any competent biologist is aware of a multitude of problems yet unresolved and of questions yet unanswered. After all, biologic research shows no sign of approaching completion; quite the opposite is true. Disagreements and clashes of opinion are rife among biologists, as they should be in a living and growing science. Antievolutionists mistake, or pretend to mistake, these disagreements as indications of dubiousness of the entire doctrine of evolution. Their favorite sport is stringing together quotations, carefully and sometimes expertly taken out of context, to show that nothing is really established or agreed upon among evolutionists. Some of my colleagues and myself have been amused and amazed to read ourselves quoted in a way showing that we are really antievolutionists under the skin.
Theodosius Dobzhansky (1973) Nothing in Biology Makes Sense Except in the Light of Evolution, 1973 
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
Francis Crick (1966) Of Molecules and Men. p. 10.
You can’t fight biology. Only push at the rules, here and there.
David Brin, Glory Season (1993), chapter 5