Brno, Czech Republic

Genomics and Proteomics

Genomika a proteomika

Language: Czech Studies in Czech
Subject area: biology
University website: www.muni.cz/
Years of study: 4
Genomics
Genomics is an interdisciplinary field of science focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes. In contrast to genetics, which refers to the study of individual genes and their roles in inheritance, genomics aims at the collective characterization and quantification of genes, which direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in genomics have triggered a revolution in discovery-based research and systems biology to facilitate understanding of even the most complex biological systems such as the brain.
Genomics
Three important research developments have made the genomic and proteomic approaches possible. One is “high-throughput” technology, tools that can analyze many biological samples very rapidly. The second major development is bioinformatics, the use of computational tools to store, organize, and analyze the huge volume of data that results from high-throughput methods. The third development is the formation of interdisciplinary research teams—groups of diverse specialists that may include computer scientists, mathematicians, engineers, chemists, physicists, and, of course, biologists from a variety of fields.
Jane B. Reece, Lisa A. Urry, et al. Campbell Biology (10th ed., 2014), Ch. 1. Evolution, the Themes of Biology, and Scientific Inquiry
Genomics
The entire “library” of genetic instructions that an organism inherits is called its genome. A typical human cell has two similar sets of chromosomes, and each set has approximately 3 billion nucleotide pairs of DNA. If the one-letter abbreviations for the nucleotides of a set were written in letters the size of those you are now reading, the genetic text would fill about 700 biology textbooks.
Jane B. Reece, Lisa A. Urry, et al. Campbell Biology (10th ed., 2014), Ch. 1. Evolution, the Themes of Biology, and Scientific Inquiry
Genomics
Changing animals by putting human genes or cells into their structure is one way of making them more resemble the bit of the human condition you're interested in studying.
Martin Bobrow Medical Research Humans Animals Regulation
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