Moscow, Russia

Computational Biology of Regulation of Transcription Initiation

Language: English Studies in English
Subject area: computer science
University website: mipt.ru/english/
4 years
Biology
Biology is the natural science that involves the study of life and living organisms, including their physical structure, chemical composition, function, development and evolution. Modern biology is a vast field, composed of many branches. Despite the broad scope and the complexity of the science, there are certain unifying concepts that consolidate it into a single, coherent field. Biology recognizes the cell as the basic unit of life, genes as the basic unit of heredity, and evolution as the engine that propels the creation of new species. Living organisms are open systems that survive by transforming energy and decreasing their local entropy to maintain a stable and vital condition defined as homeostasis. See glossary of biology.
Computational Biology
Computational biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems. The field is broadly defined and includes foundations in biology, applied mathematics, statistics, biochemistry, chemistry, biophysics, molecular biology, genetics, genomics, computer science and evolution.
Regulation
Regulation is an abstract concept of management of complex systems according to a set of rules and trends. In systems theory, these types of rules exist in various fields of biology and society, but the term has slightly different meanings according to context. For example:
Regulation
I would take to be quite a fool any man who would make a book full of laws and statutes for an apple tree telling it how to bear apples and not thorns, when the tree is able by its own nature to do this better than the man with all his books can describe and demand.
Martin Luther, Temporal Authority: To What Extent It Should Be Obeyed (1523), in Luther's Works, vol. 45 (1962), p. 89
Regulation
Will one of you gentlemen tell me in what civilized country of the earth there are important government boards of control on which private interests are represented? Which of you gentlemen thinks the railroads should select members of the Interstate Commerce Commission?
Attributed to Woodrow Wilson, at a meeting of bankers and the president shortly before he asked Congress to enact legislation creating a Federal Reserve System; reported in Carter Glass, An Adventure in Constructive Finance (1927, reprinted 1975), chapter 7, p. 116. This appears to be the origin of what is frequently quoted as: "You don't put robbers to work in a bank".
Biology
Today, nearly all biologists acknowledge that evolution is a fact.
Neil A. Campbell, Biology 2nd ed., 1990, Benjamin/Cummings, p. 434
Understanding the relationship between climate and ecosystems is crucial to preventing undesired changes to our environment, such as desertification and the loss of species. However, the multi-component and multi-scale nature of ecosystems makes them difficult to easily understand.
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