A disease is any condition which results in the disorder of a structure or function in a living organism that is not due to any external injury. The study of disease is called pathology, which includes the study of cause. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by external factors such as pathogens or by internal dysfunctions, particularly of the immune system, such as an immunodeficiency, or by a hypersensitivity, including allergies and autoimmunity.
Climate change impacts, such as rising temperatures, prolonged droughts and extreme precipitation, are expected to affect many areas, including mountain regions. A large consortium worked to develop advanced models to quantify and predict the impact of climate change primarily on surface water.