A disease is any condition which results in the disorder of a structure or function in a living organism that is not due to any external injury. The study of disease is called pathology, which includes the study of cause. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by external factors such as pathogens or by internal dysfunctions, particularly of the immune system, such as an immunodeficiency, or by a hypersensitivity, including allergies and autoimmunity.
Sea ice distribution and sea surface temperature (SST) in the North Atlantic have affected Europe's weather and climate by determining precipitation and wind patterns, and changes in temperature. Knowledge of these factors and how they will alter over the coming years is vital for society and the economy, which need accurate data for planning and decision making.