A disease is any condition which results in the disorder of a structure or function in a living organism that is not due to any external injury. The study of disease is called pathology, which includes the study of cause. Disease is often construed as a medical condition associated with specific symptoms and signs. It may be caused by external factors such as pathogens or by internal dysfunctions, particularly of the immune system, such as an immunodeficiency, or by a hypersensitivity, including allergies and autoimmunity.
Scientists use ever-more sophisticated numerical models to understand the mechanisms that shape Earth's climate and predict how it is likely to evolve. An EU-funded project is boosting Europe's contribution to this on-going international research effort and facilitates the distribution and exploitation of model data.